Alternate structures
Z-DNA and B-DNA only has been observed as Alternate structures in functional organisms directly, DNA is present in a possible conformation of many, including DNA, the Z-DNA form and B-DNA. Chemical modification amount and direction hydration level, DNA sequence, the supercoiled, of a base will depend on the nature and concentration of the presence of polyamines of metal ions in solution in the structure that receives the DNA.
Alternate structures convert that are used in the analysis on the Patterson and provide a limited amount of structural information for oriented fibers of DNA – B-DNA and – report released the first X-ray diffraction of DNA. Then, for the pattern of DNA fibers hydrated very in terms of Bessel function power X-ray diffraction / scattering in vivo B-DNA, 1953 year assay An alternative has been proposed Wilkins, etc. In the same magazine, Francis Crick and James Watson announced the molecular modeling analysis of the DNA-ray diffraction that the structure is a double helix. But is most common in the conditions found in cells “DNA, type B”, the structure is not clearly defined, the DNA associated occur at high levels of moisture present in the cell that is alive A family of conformation. Scattering properties of molecular paracrystals with the severity of the disease and X-ray diffraction pattern of each.
Compared with DNA-B,DNA alternate structure form is shallow, narrow and wide minor groove, and deep main grooves, is a right-handed spiral wide. In embodiments, the non-physiological conditions of the partially dehydrated samples of DNA in cells, can be produced with the enzyme-DNA complexes and combinations of RNA strand hybrid and DNA. Structure is changed significantly segments of DNA modified by methylation chemically, in this case may take the form Z., base, strands about the helical axis in the opposite left hand spiral and B more general form I turn. Abnormal These structures can be can be recognized by Z-DNA-binding protein specific and involved in the regulation of transcription.
The primary structure comprises a linear sequence of nucleotides which are linked together by phosphodiester bonds. This is the linear sequence of nucleotides that make up the basic structure of the RNA or DNA. Nucleotide consists of three:. Guanine and adenine nitrogen base is a purine structure, cytosine that forms the bond between the 9 ‘-OH groups of the deoxyribose and glycoside 9 “nitrogen of them, uracil and thymine Thus pyrimidine, forming the glycosidic bond of the 1-OH deoxyribose between “9 and N”. both the purine and pyrimidine bases, groups that were negatively charged phosphate group, 10 “-OH sugar and oxygen I to form a bond with the deoxyribose sugar via an ester bond between. Is derived from the nitrogen atom and the oxygen polarity in the main chain in the RNA or DNA. Is formed where acid that has been collected by phosphodiester bonds between the carbon atoms of the 5 ‘and 3’ nucleotide nucleic acid [3]. Nucleic acid is of the order of nucleotide RNA, which is determined by an array of characters or DNA (GACT) of (GACU) molecule. As shown in the 3 ‘end’ of 5, sequence defines the covalent structure of the entire molecule. The base of each item, the sequence can be added in reverse order is added to the other sequences. This is an example of TCGA sequence complementary to the AGCT. Includes both of the antisense strand DNA, a sense strand, and is double-stranded. Thus, sequence complementary would be the sense strand.
Secondary structure, that is, part of the thread is a set of interactions between bases are connected to each other. In the double helix DNA, double strand DNA, is held together by hydrogen bonds. Nucleotide base pairs of the one strand of which has a nucleotide chain other. The secondary structure, is responsible to the form on the assumption nucleic acid. Bases in DNA are classified as purines and pyrimidines. Is a guanine and adenine of pudding. Consists of a double ring structure, purine, 6-membered 5-membered nitrogen-containing ring. It is thymine and cytosine in pyrimidine. It has a 6-membered ring containing cyclic structure, the nitrogen. The secondary structure of DNA, pair (cytosine (C), and guanine and adenine (G) vs. (A), thymine or uracil (T) and (U) pyrimidine base, two polynucleotide chains wrapped in the main purine base is to form a double helix before and after each other always pair is determined on a consolidated basis. I have a minor groove of the double helix and large curve.
Taking space constraints and considerations geometrical tertiary structure is the arrangement of atoms in three-dimensional space. Secondary structure folding of large linear polymer occurs, the whole chain is folded into three box-like specific higher. Well, there are four areas form structure of the DNA be different. The quaternary structure of nucleic acids is the same as the following four structural proteins. Although not exactly the same, some of the terms, but the quaternary structure refers to a high level of organization of nucleic acids. Further, the other molecules on the interaction of the nucleic acid. Can be seen in the form of chromatin to bring the interaction form seen most commonly in the tissues of the higher level of nucleic acid, and small histone proteins. In addition, quaternary structure refers to the interaction between units in different spliceosome or ribosomal RNA.