To 5′ nucleotide of each RNA and number 1, carbon contains a ribose sugar. Adenine (A), cytosine (C), guanine (G), or the (U), as a whole, the base is attached to the position 1 ‘. Guanine and adenine is a purine pyrimidine, cytosine, and uracil. To the 3-position of the next and 5 ‘position of the ribose’ is attached to a phosphate group. Phosphate group are charged the charged RNA molecules (polyanion) all physiological pH to negative. Foundation may between the uracil and guanine and between adenine and uracil to form a hydrogen bond between guanine and cytosine. However, other interactions may be connected to each other there tetraloop GNRA, guanine, adenine at base pairs or larger groups as adenine base.
Important structural features of RNA and DNA distinction is the presence of two hydroxyl groups’ position sugar, of ribose. The presence of such functional groups causes the adoption spiral non-geometric form DNA-B type is most frequently observed. This lead to minor groove is wide and shallow and very deep, narrow major groove. The results of the second in the presence of 2′-hydroxyl group, region flexible, main profile chemically cleaved it structurally RNA molecule (i.e., is not participating in formation of the double helix) of It is to attack the phosphodiester bond adjacent to the chain.
The RNA, was transferred to (adenine, cytosine, and guanine) four bases, but sugars are connected with these databases can be varied in many ways, such as the mature RNA. Shoe copper lysine has been changed to CC bond from the CN bond and (Ψ), where another bond between the ribose and uracil (the most notable of which is a TΨC loop of tRNA) ribothymidine (T) is I am located in. Modified bases remarkable Another is deaminated adenine nucleoside base hypoxanthine and inosine are called as (I). Inosine, plays an important role in the oscillation hypothesis of the genetic code.
Nucleoside and 2′-O-methylribose often present in the rRNA and shoe copper lysine has modified nucleoside present in other natural more than 100 people, that you find, and can structure the biggest correction since mRNA various It is the most common. Specific roles of many of these changes in RNA is not fully understood. However, many of the post-transcriptional modification, for example, the peptidyl transferase center, and interfacing subunits which means that it is important for the normal function, ribosomal RNA is found in the functional region number. Such as a protein, a functional form of the single-stranded RNA molecule should be noted, require a specific conformation often. Is provided by the secondary structural elements that scaffold intramolecular hydrogen bonding of the structure. Sharp lines, and this has, a recognizable “domains” of some of the secondary structure, such as internal projection loop. RNA is is charged, metal ions such as Mg2 example is required to stabilize the secondary and tertiary structure of the number.
Guanine nitrogen bases and adenine is a purine in the structure, glycoside 9 thereof “. Cytosine which forms a bond between the 9 ‘-OH groups of the deoxyribose and nitrogen, uracil and thymine Thus pyrimidine,” “has formed glycosidic bond of the 1-OH deoxyribose between. both the purine and pyrimidine bases, phosphate groups, negatively charged groups, 10 and oxygen” and 9 N esters between-OH sugar I want to form a bond with the deoxyribose sugar via a coupling. Is derived from the nitrogen atom and the oxygen polarity in the main chain in the RNA or DNA. Where acid that has been collected by the phosphodiester bonds between the carbon atoms of the 5 ‘and 3’ is formed nucleic acid nucleotide. RNA, which is determined by the character set of the order of nucleotides in the DNA or (GACT) nucleic acid sequence is (GACU) molecule. Presents from the 3 ‘end of’ sequence 5 defines the share structure of the whole molecule. In terms of base for each item, a sequence was added in reverse order is added to the other sequences. It is able to Examples TCGA AGCT of complementary sequence. For including both of the antisense strand DNA, the sense strand, is a two-stranded, complementary sequence is a sense strand.
Secondary structure, that is, part of the thread is a set of interactions between bases are connected to each other. In the double helix DNA, double strand DNA, is held together by hydrogen bonds. Nucleotide base pairs of the one strand of which has a nucleotide chain other. The secondary structure, is responsible to the form on the assumption nucleic acid. Bases in DNA are classified as purines and pyrimidines. Is a guanine and adenine of pudding. Consists of a double ring structure, purine, 6-membered 5-membered nitrogen-containing ring. It is thymine and cytosine in pyrimidine. It has a 6-membered ring containing cyclic structure, the nitrogen. The secondary structure of DNA, pair (cytosine (C), and guanine and adenine (G) vs. (A), thymine or uracil (T) and (U) pyrimidine base, two polynucleotide chains wrapped in the main purine base is to form a double helix before and after each other always pair is determined on a consolidated basis. I have a minor groove of the double helix and large curve.
RNA secondary structure comprises a polynucleotide. Base pairs of RNA RNA occurs when it is folded with the complementary regions. In many cases, both the double-stranded region and the single strand, found in RNA molecules. I form the spiral shape of the anti-parallel chain. The main four elements of secondary structure of the helix junction of RNA, loop, and bulge,. Hairpin loop or stem-loop is the most common elements of secondary structure of RNA. RNA strands to form a stem-loop when folded by itself to form a double helical path called stop unpaired nucleotides forming single-stranded region, called cycles. It may be provided by experimental data bulge for secondary structure, secondary structure elements, coils, loops and RNA. Double helix path is formed chains of both the unpaired nucleotide or (below) from each chain (inland) internal lines and bulges divided. Tetraloop is a hairpin RNA structure of 4 bp. There is a major family of three tetraloop in ribosomal RNA. CUUG UNCG, and GNRA (N is one of the one nucleotide 4, R is a purine) UNCG is stable t etraloop most. Pseudoknot is a secondary structure of RNA is identified by the first turnip yellow mosaic virus. Single-stranded hairpin area is formed where pseudoknot to form a base pair segment of a sharp line is twisted outside. I characterized the pseudoknot folding of H-type. I form a loop and H-type fold nucleotide to the second stem with a sharp outline with offices in hairpin stem outside. This results in the formation of a pseudoknot with loop handles two convex. Pseudoknot is a functional component in most classes of RNA structure and RNA with various functions. DotKnot-PW method is used for comparison pseudoknot prediction. The main point in DotKnot-PW method, pointed out the similarities found in the H-type pseudoknot stem, and secondary element.